Resect and discard: Is it ready or time to shift gear?

Resect and Discard Strategy: Why?

Introduction The prevalence of colorectal neoplasms is approximately 30-40% in asymptomatic average-risk Koreans, which is comparable with the rate in Western countries. Although colonoscopic polypectomy can decrease the incidence of colorectal cancer, polypectomy and the ensuing pathologic examinations are major determinants of the cost. However, pathologic examinations are used only for deter...

vertical gastric plication: is it ready for prime-time?

New Paradigms for Colonoscopic Management of Diminutive Colorectal Polyps: Predict, Resect, and Discard or Do Not Resect?

The possibility to predict in vivo the histology of colorectal polyps by advanced endoscopic imaging has resulted in the implementation of a more conservative management for diminutive lesions detected at colonoscopy. In detail, a predict-and-do-not-resect strategy has been proposed for diminutive lesions located in the rectosigmoid tract, whilst a predict-resect-and-discard policy has been adv...

FGF23: is it ready for prime time?

Since the identification of fibroblast growth factor 23 (FGF23) more than a decade ago, interest in this hormone has grown dramatically among both nephrologists and endocrinologists. FGF23, initially identified in patients with rare forms of hypophosphatemia, is also increased in patients with chronic kidney disease (CKD). A handful of studies have suggested that increased circulating concentra...

Ginger: is it ready for prime time?

On the basis of substantial preclinical data showing the preventive efficacy of ginger and its constituents in vitro and in animal models, as well as a phase I pilot trial indicating that ginger extract is well tolerated in humans, Citronberg and colleagues conducted a pilot trial of ginger extract (2 g/day for 28 days) on biomarkers of cell proliferation [human telomerase reverse transcriptase...